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Vitex negundo        

  Latin Name Vitex negundo; Vitex trifolia             
English Name Five Leaved Chaste Tree; Chinese Chaste Tree
Hindi Name Nirgundi
Part Used Leaf, Seed    

1Vitex negundo is a large, aromatic shrub with quadrangular, densely whitish, tomentose branchlets. Its principal constituents are casticin, isoorientin, chrysophenol D, luteolin, p –hydroxybenzoic acid and D-fructose.

2Significant anti-arthritic activity was observed in the polyarthritis test in rats and this was associated with significant suppression of inflammatory mediators and T-cell-mediated cytokines (Th1/Th2). The anti-inflammatory activity in rats confirmed that the effect of Nirgundi is not mediated by the pituitary-adrenal axis. Nirgundi extract also showed inhibition of vascular permeability and leukocyte migration in vivo

Nirgundi is main Vatahar-Vata pacifying herb in Ayurveda. It cleanses Ama from joints & muscles and helps improve flexibility of joints.



1. Database on medicinal plants, CCFRAS, Dept. of ISM & H, Ministry of Health and Family Welfare Govt. of India, Vol-3, Page-450-455

2. PMID: 22228102, Inflamm Res. 2012 Jan 8

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